Younes Smani have a broad background in antimicrobial resistance, bacterial virulence and treatments, with specific training and expertise in molecular and cellular biology and in animal models of infection. During my doctoral studies, I investigated patterns of hemoglobin-based oxygen carrier (HBOC) side effects, and the interaction between HBOC and vascular reactivity mechanisms. As postdoc my research centered on the pathogenicity of Gram-negative bacilli (GNB), especially the study of cellular and molecular mechanisms involved in their interaction with host cell. I have also developed new projects resulting in the identification of new virulence factors of GNB, and the development of inhibitors that block these virulence factors, as a nonantimicrobial approach for multidrug-resistant bacteria therapy. In 2016 and 2021 I got Miguel Servet tipo I (MSI) and tipo II (MSII) grants (ISCIII) in the Institute of Biomedicine of Seville (IBiS) where I develop my research lines focused in the bacterial pathogenesis, new antimicrobial resistance mechanisms and antimicrobial and repurposing drugs treatment. Since 2022 I got a Professor position in Pablo de Olavide University and Principal Investigator (PI) in the Andalusian Centre for Developmental Biology (CABD) where I continue with the development of my research lines. My research has been always interdisciplinary (infectious diseases, microbiology, molecular and cellular biology), and highly collaborative. My research activity thus far has resulted in successful funding of grants and projects, and the establishment of a network of collaborators worldwide. I have produced 61 publications, 43 as first or last and/or corresponding author. My International experience is remarkable including two postdoctoral stays: one year at Nancy University (France), and 8 years postdoc at IBiS (Spain).
Biography:
Younes Smani
Pablo de Olavide University Sevilla
Younes Smani have a broad background in antimicrobial resistance, bacterial virulence and treatments, with specific training and expertise in molecular and cellular biology and in animal models of infection. During my doctoral studies, I investigated patterns of hemoglobin-based oxygen carrier (HBOC) side effects, and the interaction between HBOC and vascular reactivity mechanisms. As postdoc my research centered on the pathogenicity of Gram-negative bacilli (GNB), especially the study of cellular and molecular mechanisms involved in their interaction with host cell. I have also developed new projects resulting in the identification of new virulence factors of GNB, and the development of inhibitors that block these virulence factors, as a nonantimicrobial approach for multidrug-resistant bacteria therapy. In 2016 and 2021 I got Miguel Servet tipo I (MSI) and tipo II (MSII) grants (ISCIII) in the Institute of Biomedicine of Seville (IBiS) where I develop my research lines focused in the bacterial pathogenesis, new antimicrobial resistance mechanisms and antimicrobial and repurposing drugs treatment. Since 2022 I got a Professor position in Pablo de Olavide University and Principal Investigator (PI) in the Andalusian Centre for Developmental Biology (CABD) where I continue with the development of my research lines. My research has been always interdisciplinary (infectious diseases, microbiology, molecular and cellular biology), and highly collaborative. My research activity thus far has resulted in successful funding of grants and projects, and the establishment of a network of collaborators worldwide. I have produced 61 publications, 43 as first or last and/or corresponding author. My International experience is remarkable including two postdoctoral stays: one year at Nancy University (France), and 8 years postdoc at IBiS (Spain).